Gene description for HEG1
Gene name heart development protein with EGF like domains 1
Gene symbol HEG1
Other names/aliases HEG
MST112
MSTP112
Species Homo sapiens
 Experiment description of studies that identified HEG1 in Melanoma cells

1
Experiment ID617
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameLOX IMVI
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

2
Experiment ID1627
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 34012515   
OrganismHomo sapiens
Experiment descriptionCD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells
AuthorsSuárez H, Andreu Z, Mazzeo C, Toribio V, Pérez-Rivera AE, López-Martín S, García-Silva S, Hurtado B, Morato E, Peláez L, Arribas EA, Tolentino-Cortez T, Barreda-Gómez G, Marina AI, Peinado H, Yáñez-Mó M.
Journal name J Extracell Vesicles
Publication year2021
SampleMelanoma cells
Sample nameSK‐MEL‐147
Isolation/purification methodsDifferential centrifugation
Centrifugal ultrafiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyLC-MS/MS
MALDI-MS
Western blotting
EV-TRACK -

3
Experiment ID1628
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 34012515   
OrganismHomo sapiens
Experiment descriptionCD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells
AuthorsSuárez H, Andreu Z, Mazzeo C, Toribio V, Pérez-Rivera AE, López-Martín S, García-Silva S, Hurtado B, Morato E, Peláez L, Arribas EA, Tolentino-Cortez T, Barreda-Gómez G, Marina AI, Peinado H, Yáñez-Mó M.
Journal name J Extracell Vesicles
Publication year2021
SampleMelanoma cells
Sample nameSK‐MEL‐147
Isolation/purification methodsDifferential centrifugation
Centrifugal ultrafiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyLC-MS/MS
MALDI-MS
Western blotting
EV-TRACK -

<